International Science and Engineering Fair



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Regeneron International Science and Engineering Fair

The 2024 Regeneron International Science and Engineering Fair will take place between May 11 and 16 in Los Angeles, California

Rules, Regulations, Forms and Judging Criteria
The Rules and Regulations Handbook is available here

A list of the required forms can be found here.
The Criteria for ISEF judging is available here.

Selection of Students
Four students whose exhibits are judged to be Outstanding will be selected to attend the International Science and Engineering Fair.  Expenses for the international fair will  be paid by The Chicago Public Schools Student Science Fair, Inc.  Rules and accompanying forms are available electronically for student use at the website.

Continuation of Projects

Students will be judged only on the most recent year’s research. This project year includes research conducted over a maximum of 12 continuous months from June 2023 to May 2024. Any project in the same field of study from a previous year’s project is considered a continuation. These projects must document that the additional research is new and different from prior work (e.g., testing a new variable or new line of investigation, etc.). Repetition of previous experimentation or increasing sample size are examples of unacceptable continuation. For competition in the ISEF, documentation must include the Continuation Project Form (7), the prior year’s Abstract and Research Plan (1A). Copies must be attached behind the current year’s Research Plan (1A), Research Plan Attachment, and necessary forms.


Patent and Copyright Information
You may want to consider applying for a patent or copyright if you want to protect your work. You can contact the Office of Public Affairs, U.S. Patent Office, at (800) 786-9199 for patent information, or the Library of Congress at (202) 707-3000 for copyright information.

Additional information can be obtained from the following two libraries that serve as patent depositories in Illinois: The Illinois State Library in Springfield; and the Harold Washington Library of the Chicago Public Library system (Science and Technology, 4th Floor).

Excerpts from Basic Facts About Patents
(Note: An examination copy of this booklet is available at the Harold Washington Library.)

What is a patent?
A patent is granted by the federal government to an inventor “to exclude others from making, using, offering for sale, or selling the invention throughout the United States or importing the invention into the United States.” There are three types of patents:

Utility patents may be granted to anyone who invents or discovers any new and useful process, machine, article of manufacture, composition of matter, or any new useful improvement thereof.
Design patents may be granted to anyone who invents a new, original, and/or ornamental design for an article of manufacture.
Plant patents may be granted to anyone who invents or discovers and asexually reproduces any distinct and new variety of plant.

Answers to the following questions can be answered by reading Basic Facts About Patents.

How long does patent protection last?
Who owns the patent rights?
How do I get a patent?
Do I need to hire a lawyer?
What about patent promotion organizations?
How do I get help marketing my invention?
Is my patent good in foreign countries?
Do I need to do a patent search before I apply?

ISEF Sources of Information
Code of Federal Regulation (CFR), Title 45 (Public Welfare), Part 46- Protection of Human Subjects (45CFR46)
Penslar, R.L., Institutional Review Board (IRB) Guidebook. (1993). Washington, DC:

Office for Human Research Protections
Department of Health and Human Services
The Tower Building
1101 Wootton Parkway, Suite 200
Rockville, MD 20852
Phone: (301) 496-7005

Federal Animal Welfare Act (AWA)
Quick Reference Guide
Regulatory Enforcement & Animal Care
U.S. Department of Agriculture
12th & Independence Avenue, SW
Washington, DC 20250

Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching (Agri-Guide)
Federation of Animal Science Societies (FASS)
1111 N. Dunlap Avenue
Savoy, IL 61874
Phone (217) 356-3182

Euthanasia Guidelines
2000 Report of the AVMA Panel of Euthanasia.
Journal of the American Veterinary Medical Association (JAVMA), Vol. 218, No.52:669-696, March 2001.

John Hopkins Center for Alternatives to Animal Testing (CAAT) has worked with scientists since 1981 to find new methods to replace the
use of laboratory animals in experiments, reduce the number of animals tested, and refine necessary tests to eliminate pain and distress.

Biosafety in Microbiological and Biomedical Laboratories (BMBL) – 4th Edition
Published by CDC-NIH
2006 Science Fair Handbook 39
To order, contact:
Office of Health and Safety
Centers for Disease Control and Prevention
1600 Clifton Road, NE mailstop F05
Atlanta, GA 30333
See also:

Safety in Academic Chemistry Laboratories, 1995. Washington, DC: American Chemical Society
American Chemical Society
Publications Support Services
1155 15th Street, NW
Washington, DC 20036
Phone: (202) 872-4554 or (800) 227-5558


Prescription Drugs
Superintendent of Documents
U.S. Government Printing Office
Washington, DC 20402
Phone: (202) 512-1800


NIH Guidelines for Research Involving Recombinant DNA Molecules
Published by National Institutes of Health

Microorganisms for Education Safety

Sources for Animal Tissue Cultures
Carolina Biological Supply Company
Main office and Laboratories
2700 York Road
Burlington, NC 27215-3398
Phone: (336) 584-0381 or (800) 335-5551

American Type Culture Collection/Culture Guides
1081 University Boulevard
Manassas, VA 20110-2209
Phone: (703) 365-2700 or (800) 638-6597